Pioglitazone (Actos) is an oral medication used to treat Type 2 diabetes in adults, along with diet and exercise. It's a thiazolidinedione, which works by helping your body respond better to insulin. This medication is taken by mouth once a day and is available in both brand and generic forms. Pioglitazone is used with proper diet and exercise to treat high blood sugar levels caused by type 2 diabetes. It may be used alone or with other medicines such as insulin, metformin, or sulfonylurea agents. Pioglitazone works by helping your body use insulin better. ACTOS: manage field activations at retail stores. Mobile check-ins, photos, and live ops dashboard. Actos (Pioglitazone Hydrochloride) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Actos (pioglitazone) is a prescription tablet that’s used to control blood sugar levels in type 2 diabetes. Learn about side effects, dosage, uses, and more. Pioglitazone, sold under the brand name Actos among others, is an anti-diabetic medication used to treat type 2 diabetes. [3] It may be used with metformin, a sulfonylurea, or insulin. [3][4] Use is recommended together with exercise and diet. [4] Actos is an oral diabetes medicine that helps control blood sugar levels. Actos is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Learn about side effects, dosage, uses, what to consider, and more for Actos (pioglitazone), which is a prescription tablet that treats type 2 diabetes in adults. Pioglitazone is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Pioglitazone is not for treating type 1 diabetes. Pioglitazone may also be used for purposes not listed in this medication guide. Overview: Pioglitazone is a tablet you swallow that is used to help control your blood sugar levels if you have type 2 diabetes. It helps your body use insulin, a natural chemical in your body that.