Zolpidem is used to treat insomnia (trouble sleeping). It belongs to the group of medicines called central nervous system (CNS) depressants, which slows down the nervous system. Zolpidem will help you get to sleep faster and sleep throughout the night. Ambien (zolpidem) affects chemicals in the brain that may be unbalanced in people with sleep problems (insomnia). Ambien is used to treat insomnia. The immediate-release tablet is used to help you fall asleep when you first go to bed. Ambien CR uses a two-layer tablet: one layer dissolves fast for sleep onset, and a second layer releases slowly to maintain blood levels for over 6 hours. In clinical trials, Ambien CR reduced nighttime awakenings for up to 5 hours after dosing, compared to 3 hours for the standard tablet. Zolpidem (Ambien) is a medication that treats insomnia. It helps you fall asleep and stay asleep throughout the night. Ambien, with the active ingredient zolpidem, is FDA-approved to treat insomnia. It’s in a drug class with sedative/hypnotic medications. Ambien targets specific receptors in the brain that inhibit certain types of activity in the brain, which can induce and maintain sleep. Read this Ambien dosage guide with information on available forms of zolpidem, typical and maximum dosages, adjustments for health conditions, and more. Zolpidem (Ambien) is commonly used short-term to help treat insomnia. It can be used to help people fall asleep faster or help them wake up less times during the night. Ambien is a sedative-hypnotic (sleep) medicine that is used in adults for the short-term treatment of a sleep problem called insomnia (trouble falling asleep). As of September 2018, zolpidem is marketed under many brands, examples include: Ambien 5 mg & 10 mg (IR oral tablets), Ambien CR 6.25 mg & 12.5 mg (controlled release tablets), Edluar 5 mg & 10 mg (sublingual tablets), Intermezzo 1.75 mg & 3.5 mg (sublingual tablets), and ZolpiMist 5 mg (oral spray). [1][100][11] Ambien (Zolpidem) is a sedative-hypnotic (sleep) medicine. AMBIEN is used in adults for the short-term treatment of a sleep problem called insomnia. Learn about side effects, dosage, interactions, and warning.