Learn about the side effects of amitriptyline, from common to rare, for consumers and healthcare professionals. Amitriptyline HCl is an antidepressant with sedative effects. Its mechanism of action in man is not known. It is not a monoamine oxidase inhibitor and it does not act primarily by stimulation of the central nervous system. Amitriptyline hydrochloride, USP, a dibenzocycloheptadiene derivative, is a white, or practically white, odorless, crystalline compound which is freely soluble in water and alcohol. Amitriptyline may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you or your caregiver notice any of these adverse effects, tell your doctor right away. Amitriptyline Tablets Amitriptyline is a medication that treats depression. It works by increasing the amount of serotonin and norepinephrine in your brain. These hormones help regulate your mood. Brand names for this medication include Elavil® and Vanatrip®. Amitriptyline Hydrochloride was initially developed to treat depression, and it remains a staple in mental health treatment for this condition. It helps improve mood, relieve anxiety and tension, and increase energy levels. Amitriptyline is indicated for the treatment of major depressive disorder, neuropathic pain, and for the prevention of migraine and chronic tension headache. It can be used for the treatment of nocturnal enuresis in children older than 6 after other treatments have failed. [11] Amitriptyline Hydrochloride | C20H24ClN | CID 11065 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. Find patient medical information for Amitriptyline (Amitid, Elavil, Endep) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Amitriptyline is a tricyclic antidepressant used to treat depression and, off-label, conditions like insomnia, anxiety, migraines, and chronic pain.