Bactrim is a combination antibiotic medication. Bactrim can cause digestive issues and other side effects, including skin problems. Trimethoprim-sulfamethoxazole is an antibiotic used to treat various bacterial infections. Learn about uses, side effects, dosage, and more for Bactrim. It's a prescription oral tablet used to treat certain types of infection in adults and some children. Find patient medical information for Sulfamethoxazole/Trimethoprim (Bactrim, Septra, others) on WebMD including its uses, side effects and safety, interactions. Bactrim (Trimethoprim and Sulfamethoxazole) may treat UTI, side effects, dosage, drug interactions, warnings, patient labeling, and more Bactrim DS- sulfamethoxazole and trimethoprim tablet; Bactrim- sulfamethoxazole and trimethoprim tablet [package insert]. DailyMed. GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Bactrim (sulfamethoxazole and trimethoprim) is an antibiotic used to treat ear infections, urinary tract and other infections. Includes Bactrim side effects, interactions and indications. Description Sulfamethoxazole and trimethoprim combination is used to treat infections including urinary tract infections, middle ear infections (otitis media), bronchitis, traveler's diarrhea, and shigellosis (bacillary dysentery). This medicine is also used to prevent or treat Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP), a very serious kind of pneumonia. This type. Trimethoprim/sulfamethoxazole, sold under the trade names Bactrim, Cotrim (a short form of the British Approved Name, Co-trimoxazole) and Septra, among others, is a fixed-dose combination antibiotic medication used to treat a variety of bacterial infections. [2] Bactrim is a combination antibiotic used to treat infections caused by susceptible bacteria affecting the urinary tract infections, ear (otitis media), lungs (acute exacerbations of chronic bronchitis in adults, pneumocystis jirovecii pneumonia), and intestines (shigellosis and traveler's diarrhea in adults).