Wondering if it’s safe to take Benadryl every day? Learn about the risks, side effects and safer options for managing your allergies and sleep issues. Benadryl (diphenhydramine) is a brand-name over-the-counter drug that’s used for allergies and itchy skin. Learn about side effects, price, and more. Yes, Benadryl is effective for allergies as it contains an antihistamine, which blocks histamines, the compounds causing allergy symptoms. It provides relief from sneezing, runny nose, itchy eyes, and hives. Benadryl is an antihistamine and is used to treat sneezing, runny nose, itching and other allergies. Learn about side effects, interactions and indications. Use BENADRYL ® Allergy ULTRATABS ® Tablets with 25 mg of diphenhydramine HCI, which are antihistamine allergy tablets, for effective relief from both indoor and outdoor allergies. Explore our range of BENADRYL® adult allergy medications. Find effective relief from allergy symptoms like sneezing, runny nose, and itchy eyes. Benadryl products that are taken by mouth are used to treat allergy symptoms such as sneezing, itchy/watery eyes, runny nose, and itchy nose and throat. Some Benadryl products may also. Benadryl treats allergy symptoms like sneezing, runny nose, and itchy skin. It is also used short-term as a sedating antihistamine—not as a long-term sleep plan. Benadryl Allergy is an antihistamine that is used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching, and other cold or allergy symptoms. Benadryl Allergy is also used to treat motion sickness, to induce sleep, and to treat certain symptoms of Parkinson's disease. But as newer antihistamines have become available over the past two decades, first-generation medications like Benadryl are no longer recommended for regular allergy treatment.