Relieve minor pain and itching from outdoor activities with Benadryl Extra Strength Itch Relief Cream, with 2% diphenhydramine and 0.1% zinc acetate for ages 2+. Formulated with 2% diphenhydramine HCI topical analgesic, this soothing anti-itch gel blocks the histamine that causes discomfort. It temporarily relieves pain and itching associated with insect bites, mosquito bites, scrapes, minor burns, sunburns, minor skin irritations, cuts and scrapes. Keep your skin comfortable with Benadryl anti-itch cream from CVS Pharmacy. Benadryl cream helps soothe pain and alleviate itching from allergies, contact dermatitis, insect bites, sunburn and other causes. Get relief from minor pain and skin itching caused by most outdoor itches with Benadryl Extra Strength Itch Stopping Anti-Itch Cream. They come in cream, gel, and spray forms, and temporarily relieve itching and pain on the skin. It is important to read labels carefully and follow the instructions for use. Discover topical skin, rash and pain relief with BENADRYL® Extra Strength Itch Stopping Cream for bug bites, sunburn, poison ivy rash, and other minor skin irritations. Get relief from minor pain and skin itching caused by most outdoor itches with Benadryl Extra Strength Itch Stopping Anti-Itch Cream. Itchy skin relief: should you reach for Benadryl cream or hydrocortisone? GoodRx compares the two creams to help you choose the best treatment for fast relief. DIPHENHYDRAMINE (dye fen HYE dra meen) reduces pain, itching, swelling, or rashes caused by skin conditions such as insect bites and sunburns. It works by blocking histamine, a substance released by the body during an allergic reaction. It belongs to a group of medications called antihistamines. Overview: Topical diphenhydramine is used to treat minor skin pain, itching, burns, and rashes. It works by blocking a natural substance called histamine. Topical diphenhydramine can make your.