Monitor for bradycardia, respiratory depression. Whether a rate control or rhythm control strategy is chosen is very specific to each individual patient. Factors to consider are: ability to tolerate medications, degree of symptoms, degree of functional limitation, occupation, age, and other co-morbidities. Patients at immediate risk of suicidal ideations: preferred drug in these patients. - Good choice for concomitant insominia. May involve dietary restrictions for foods rich in tyramine due to potentially fatal interaction. - Traditionally considered to be last line alternatives. For patients with AF and either intermediate or high risk of stroke, oral anticoagulation is recommended. For patients who are not suitable for or choose not to take an anticoagulant (for reasons other than concerns for major bleeding), the combination of aspirin (75. 2 to 325 mg daily) and clopidogrel is suggested. The decision of whether to employ a loading dose, as well as the magnitude of this dose, should be driven by the severity of infection and the urgency to achieve a therapeutic concentration rather than body size alone. InsightRX has a loading dose feature that can help simulate exposure. SHC Antibiotic Dosing Guide and SHC Obesity Dosing Guide for renal and obesity dose adjustments Inhibits CP450- 2D6, May cause GI distress, discontinuation syndrome. Effective for neuropathic pain. Serum drug levels can guide dosing.