When paired with therapy and healthy coping strategies, Prozac can be a safe and effective part of your anxiety treatment plan, helping you achieve lasting relief and a better quality of life. Prozac is a selective serotonin reuptake inhibitor (SSRI) antidepressant. Fluoxetine affects certain chemical messengers (neurotransmitters) that communicate between brain cells and helps people with depression, panic, anxiety, or obsessive-compulsive symptoms. Prozac (fluoxetine) is an FDA-approved treatment for panic disorder and obsessive-compulsive disorder, and it’s widely prescribed for generalized anxiety, social anxiety, and PTSD. Prozac (fluoxetine) is a selective serotonin reuptake inhibitor (SSRI) antidepressant medication that can be used to treat anxiety in addition to depression. Learn how Prozac (fluoxetine) is used for anxiety, how it works, its benefits and side effects, and when it may be the right treatment option for you. Along with other SSRI medications, Prozac has the benefit of not being habit-forming, so it can be used long-term to treat anxiety disorders. It is usually taken once daily, and there is a generic option available. Prozac (fluoxetine) is an effective SSRI that helps treat various anxiety disorders, especially panic disorder and generalized anxiety. It works by increasing serotonin levels in the brain to stabilize mood and reduce anxious thoughts. Some people taking fluoxetine may have anxiety, nervousness, or trouble sleeping (insomnia). Talk with your health care provider if you have changes to your sleep or you feel more anxious or. Prozac (fluoxetine) is an antidepressant in the SSRI family that can also help treat anxiety and is often recommended as a first-line treatment strategy from mental health professionals. According to the U.S. National Library of Medicine, clinical studies of Prozac show it to be effective in managing symptoms of certain anxiety disorders such as panic disorder.