Learn about the side effects of Zyrtec (cetirizine), from common to rare, for consumers and healthcare professionals. Zyrtec and Claritin are used to treat allergy symptoms like runny nose and sneezing. These medications generally do not significantly raise blood pressure in most users. Consult a healthcare professional if you have concerns about interactions with other medications. Lifestyle changes can be important for managing both allergies and overall health. Some allergy medications are off-limits when you have high blood pressure (aka hypertension). WebMD helps you find out which allergy drugs are OK. Some antihistamines may cause a temporary spike in blood pressure and heart rate, but they are generally safe for people with high blood pressure. Key takeaways Zyrtec, by itself, is a safe option for individuals with high blood pressure. If you have hypertension, allergy medication containing the decongestant pseudoephedrine, such as Zyrtec-D, should be avoided. Read the active and inactive ingredient list of allergy medications in order to reduce unwanted side effects. Cetirizine hydrochloride (Zyrtec) is a frequently used second-generation antihistamine that provides relief from common allergy symptoms like sneezing, itching, and watery eyes. Since millions rely on this over-the-counter medication, a key health concern is whether it affects cardiovascular health, particularly if it raises blood pressure. This article examines the drug’s properties and. Histamine can cause itching, sneezing, runny nose, and watery eyes. Decongestants produce a narrowing of blood vessels. This leads to clearing of nasal congestion, but it may also cause an increase in blood pressure in patients who have high blood pressure. This medicine is available without a prescription. Zyrtec is a brand-name over-the-counter medication used to treat allergy symptoms. In general, Zyrtec is not known to increase blood pressure. There are two main types of allergy medications: antihistamines and decongestants. If you have high blood pressure, antihistamines are generally safer to take than decongestants. Decongestants are potentially dangerous for people with high blood pressure. They can raise your blood pressure. But short courses of decongestants can be safe if a person’s hypertension is well managed with medication. Zyrtec, known generically as cetirizine, is one of the most widely used antihistamines for seasonal allergies, hives, and allergic reactions. With millions of adults experiencing chronic or intermittent high blood pressure, the question “Is Zyrtec safe if you have high blood pressure?” has become increasingly important.