Overview: Citalopram is used to treat depression. It is thought to work by increasing the amount of a natural chemical called serotonin in the brain. Common side effects may include nausea, changes. Take this medicine only as directed by your doctor, to benefit your condition as much as possible. Celexa (citalopram) is a prescription drug that treats depression in adults. Learn about side effects, Celexa vs. Lexapro, dosage, withdrawal, and more. Celexa is a selective serotonin reuptake inhibitor (SSRI) that blocks the reuptake of serotonin (5-HT) by the nerves of the central nervous system, which enhances serotonergic activity. Citalopram (Celexa) is a medication that treats depression. It increases the amount of serotonin in your brain. Celexa (citalopram) is a brand-name drug that’s used to treat depression in adults. Celexa comes as a tablet that you swallow. Learn about side effects, dosage, uses, and more. Citalopram, sold under the brand name Celexa among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [7][9] It is used to treat major depressive disorder, obsessive–compulsive disorder, panic disorder, and social anxiety disorder. [7] Citalopram (Celexa) is a first-choice medication for treating depression in adults. This antidepressant belongs to the drug class called selective serotonin reuptake inhibitors (SSRIs). Citalopram is a prescription medicine used in adults to treat depression. Citalopram is also used to treat major depressive disorder (MDD). Citalopram belongs to a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs). Celexa (citalopram hydrobromide) used to treat the symptoms of depression. Learn side effects, dosage, drug interactions, warnings, patient labeling, reviews, and more.