The daily dose usually starts at 2.5 mg and may be increased to 5 mg based on effectiveness and tolerability. When taken as needed, the typical dose is 10 mg at least 30 minutes before sexual activity, which can be increased to 20 mg if necessary. For as-needed use, start with tadalafil 10 mg taken prior to anticipated sexual activity, with dose adjustment to 20 mg or down to 5 mg based on tolerability. This article describes the dosages of Cialis, as well as its strengths and how to take it. To learn more about Cialis, including its cost and side effects, see this Cialis overview article. The maximum recommended dosage of Cialis is 20 milligrams (mg) once daily if you take it as needed to treat erectile dysfunction (ED). For all other Cialis-approved uses, the recommended maximum dosage is 5 mg once daily. How should I take Cialis? Cialis is usually taken only once per day. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Cialis can be taken with or without food. Do not break or split a tablet. Swallow it whole. If you’re taking Cialis, your dosage may be 2.5 mg to 20 mg as needed before sexual activity or once a day. But if you’re taking Adcirca, your dosage is usually 40 mg a day. For ED, Tadalafil can be taken either once per day or as needed before sexual activity, with dosages ranging from 2.5 milligrams (mg) to 20 mg. The usual daily Cialis dosage ranges from 2.5 mg to 5 mg by mouth, taken once daily. Most people start at the 2.5 mg dose, which may be increased to 5 mg based on how well it works for you. Detailed dosage guidelines and administration information for Cialis (tadalafil). Includes dose adjustments, warnings and precautions. Whether you’re considering Cialis for the first time or adjusting your dose, knowing how much to take and when can make a big difference in your results. This guide breaks down typical dosing schedules, how to adjust doses for specific conditions, and tips for safe use.