Adults generally take Cipro tablets orally twice a day. The dose typically ranges from 250 mg to 750 mg, depending on the infection being treated. The dose is usually 15 milligram (mg) per kilogram (kg) of body weight every 8 to 12 hours for 14 days. However, the dose is usually not more than 500 mg per day. For urinary tract or serious kidney infections: Adults—250 to 500 milligrams (mg) 2 times a day, taken every 12 hours for 7 to 14 days. This article describes the dosages of Cipro, as well as its strengths and how to take it. To learn more about Cipro, including its side effects and uses, see this in-depth Cipro article. Ciprofloxacin is a prescription drug used to treat certain bacterial infections. Learn about the drug’s dosages, form, strengths, and more. Detailed Ciprofloxacin dosage information for adults and children. Includes dosages for Urinary Tract Infection, Sinusitis, Bronchitis and more; plus renal, liver and dialysis adjustments. Cipro usual oral dose in adults is 250-750 mg (immediate release tablets) every 12 hours or 500-1000 mg (extended release tablets) every 24 hours. What Drugs, Substances, or Supplements Interact with Cipro? What is the standard ciprofloxacin dosage for adults? + Most adults take ciprofloxacin at doses between 250 mg and 750 mg twice daily, depending on the type and severity of the infection. A common ciprofloxacin dosage for adults is 500 mg to 750 mg every 12 hours for 7 to 14 days, but specific dosages vary by infection. Kids normally receive dosages based on their body weight. Detailed dosage guidelines and administration information for Cipro (ciprofloxacin hydrochloride). Includes dose adjustments, warnings and precautions. Medscape - Infection dosing for Cipro, Cipro XR (ciprofloxacin), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost.