Ciprofloxacin and hydrocortisone is a combination medicine used to treat otitis externa. Otitis externa, also known as Swimmer's ear, is an infection of the outer ear canal caused by bacteria. The ear canal and outer part of the ear may be swollen, red, and painful. CIPRO HC OTIC prescription and dosage information for physicians and health care professionals. Pharmacology, adverse reactions, warnings, and CIPRO HC OTICside effects. Ciprofloxacin and hydrocortisone otic (for the ear) is a combination medicine used to treat infections in the ear canal. ciprofloxacin and hydrocortisone will not treat an inner ear infection (also called otitis media). Overview: Cipro HC is an ear drop used to treat certain types of ear infections. It contains an antibiotic to kill the bacteria and a corticosteroid to help reduce swelling and discomfort from. CIPRO® HC OTIC is indicated for the treatment of acute otitis externa in adult and pediatric patients, one year and older, due to susceptible strains of Pseudomonas aeruginosa, Staphylococcus. CIPRO® HC OTIC (ciprofloxacin hydrochloride and hydrocortisone otic suspension) contains the synthetic broad spectrum antibacterial agent, ciprofloxacin hydrochloride, combined with the anti-inflammatory corticosteroid, hydrocortisone, in a preserved, nonsterile suspension for otic use. Cipro HC is a combination otic (ear drop) suspension containing ciprofloxacin (a fluoroquinolone antibiotic) and prednisone (a corticosteroid). It's used to treat outer ear infections, also known as swimmer's ear, in adults and children ages 1 year and older. CIPRO ® HC OTIC (ciprofloxacin hydrochloride and hydrocortisone otic suspension) contains the synthetic broad spectrum antibacterial agent, ciprofloxacin hydrochloride, combined with the anti-inflammatory corticosteroid, hydrocortisone, in a preserved, nonsterile suspension for otic use. Easy-to-read patient leaflet for Cipro HC. Includes indications, proper use, special instructions, precautions, and possible side effects. CIPRO ® HC OTIC (ciprofloxacin hydrochloride and hydrocortisone otic suspension) contains the synthetic broad spectrum antibacterial agent, ciprofloxacin hydrochloride, combined with the anti-inflammatory corticosteroid, hydrocortisone, in a preserved, nonsterile suspension for otic use.