Domperidone is not currently a legally marketed human drug and it is not approved for sale in the U.S. for human use. FDA issued a warning in 2004 that stated that distributing. Medscape - INDICATION dosing for domperidone, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Domperidone is not an FDA-approved drug for any indication, or use, in humans. Domperidone is approved in some countries, but not in the U.S., to treat certain gastrointestinal disorders. Find out how domperidone treats feeling sick (nausea) and vomiting, and how to take it. NHS medicines information on domperidone – what it's used for, side effects, dosage and who can take it. Domperidone is an anti-sickness medicine. It helps you to stop feeling or being sick (nausea or vomiting). It works by causing the muscles at the top of your stomach to tighten and the muscles at the bottom of your stomach to relax. This makes you less likely to be sick (vomit). Domperidone is a drug that has been prescribed to increase breast milk supply. Learn more about it, if it works, and if it's safe to use. It is used to treat stomach-related issues, such as nausea and vomiting, as well as stomach pain and discomfort caused by decreased movement of the stomach and upper gastrointestinal (GI) tract. It is also used to boost breastmilk supply. Domperidone works by blocking dopamine receptors in the gut. Domperidone is used as immunotherapy to treat leishmania in dogs. [51] Domperidone is a medicine that increases the movements or contractions of the stomach and bowel. Domperidone is also used to treat nausea and vomiting caused by other drugs used to treat Parkinson's Disease. Domperidone is to be given only by or under the immediate supervision of your doctor. What is this drug used for? It is used to treat a slow moving GI (gastrointestinal) tract in some people. It is used to prevent upset stomach and throwing up caused by drugs used for Parkinson’s disease. What do I need to tell my doctor BEFORE I take this drug?.