Display complete list of interactions for an individual item by clicking item name. Add another item to analyze for potential interactions. NOTE: This tool does not address chemical compatibility related to I.V. drug preparation or administration. Use Drugs.com’s Drug Interaction Checker, trusted by doctors and patients, to instantly review your meds for unsafe combinations. The most comprehensive drug interaction checker on the internet. Built from over a quarter million FDA drug labels and NIH data — severity-ranked results, instant autocomplete, no account needed. Site Navigation Patients and Families Medical Professionals Research Skip to main content Home Drugs, Herbs & Supplements Drug Interaction Checker A drug interaction occurs when one substance affects how another works in the body. Interactions can happen with prescription drugs, over-the-counter medicines, supplements, foods, alcohol, and certain medical conditions. Check for interactions between drugs including warnings for food, alcohol, pregnancy, breastfeeding, and diseases. Switch between consumer and professional reports. Use WebMD’s Drug Interaction Checker to identify potential interactions between medications, supplements, and foods. Reduce side effects and support safer treatment decisions. Drug Interactions Type the drug name (brand or generic) in the search field. Select the drug and click the (Add) button. Medscape's Drug Interaction Checker helps you build safer, more effective treatment plans by quickly identifying potential interactions between medications, supplements, and even common foods. Check for drug interactions and learn what drug combinations to avoid with the RxList drug interaction checker tool.