Search 24,000+ prescription, OTC, and natural medications. Peer-reviewed, clinically sourced drug information for safer, smarter health decisions. Check for drug interactions and learn what drug combinations to avoid with the RxList drug interaction checker tool. The drug interactions checker will check for interactions between the drugs you enter, any possible food or disease interactions and pregnancy / breastfeeding warnings. This tool explains what the interaction is and how it occurs, the level of importance and how to handle the drug interaction. It will also display any interactions between your chosen medicines, alcohol, food, beverages, or medical conditions. Display complete list of interactions for an individual item by clicking item name. Add another item to analyze for potential interactions. NOTE: This tool does not address chemical compatibility related to I.V. drug preparation or administration. Use WebMD’s Drug Interaction Checker to identify potential interactions between medications, supplements, and foods. Reduce side effects and support safer treatment decisions. A drug interaction occurs when one medication changes the way another medication works in your body. Interactions can increase a drug's side effects, reduce its effectiveness, or — in serious cases — cause life-threatening reactions. Medscape's Drug Interaction Checker helps you build safer, more effective treatment plans by quickly identifying potential interactions between medications, supplements, and even common foods. Use this medicine and drug interaction checker to see whether your medicines, supplements, vitamins, foods, or certain health conditions may interact with each other. A drug interaction happens when food, supplements or other drugs prevent a medication from working as it should or cause unwanted effects in your body.