Dydrogesterone was first introduced, by Duphar, as Duphaston in the United Kingdom in 1961. [15] Subsequently, it was introduced in the United States as Duphaston and Gynorest in 1962 and 1968, respectively. [15] Duphaston® Brand names may vary by country. This information refers to the product as marketed in selected countries. Duphaston is the brand name for dydrogesterone 10 mg, a tablet that mimics progesterone. It is used for irregular or absent periods, heavy bleeding, endometriosis, PMS, and to protect the womb lining during HRT. Duphaston (dydrogesterone) medicine is a type of synthetic hormone commonly used in women's health to support progesterone levels in the body. It helps regulate menstrual cycles, treat hormonal imbalances, and is often prescribed during pregnancy to prevent miscarriage. Quick Facts About Duphaston 10 mg. What is Duphaston 10 mg Tablet? Duphaston 10 mg is a prescription medicine that contains dydrogesterone, a synthetic form of progesterone-like hormone. It is commonly prescribed in women with conditions linked to low progesterone levels or hormonal imbalance. Duphaston 10mg Tablet is used to relieve the symptoms of endometriosis (a problem caused by growth of the womb lining outside the womb) and treat infertility due to low levels of progesterone. Duphaston 10mg Tablet is used to relieve the symptoms of endometriosis (a problem caused by growth of the womb lining outside the womb) and treat infertility due to low levels of progesterone. Explore Duphaston 10mg Tablet uses, benefits, dosage, and side effects. Learn how it works for hormonal imbalances, irregular periods, and pregnancy support. Duphaston Tablet works by imitating the activities of the natural hormone progesterone, which in turn helps to treat conditions caused due to hormonal imbalance in the body. Duphaston Tablet may cause side effects such as nausea, headache, abnormal vaginal discharge, breast pain and tenderness, etc. These side effects usually subside with time. Duphaston is a progestogen that works by regulating the healthy growth and normal shedding of the womb lining by acting on progesterone receptors in the uterus.