Efavirenz package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology. SUSTIVA (efavirenz) in combination with other antiretroviral agents is indicated for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults and in pediatric patients at. Efavirenz, emtricitabine, and tenofovir combination is used alone or with other anti-HIV medicines to treat human immunodeficiency virus (HIV) infection. HIV is the virus that causes acquired immune deficiency syndrome (AIDS). This medicine does not cure or prevent HIV infection or AIDS. Efavirenz (EFV), sold under the brand names Sustiva among others, is an antiretroviral medication used to treat and prevent HIV/AIDS. [1] It is generally recommended for use with other antiretrovirals. [1] Efavirenz is used to treat human immunodeficiency virus (HIV) infection. Efavirenz is in a class of medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It works by decreasing the amount of HIV in the blood. Efavirenz is a non-nucleoside reverse transcriptase inhibitor indicated in combination with other antiretroviral agents for the treatment of human immunodeficiency virus type 1 infection in. It works by lowering the amount of HIV in the blood and helps the immune system. This may help delay some of the medical conditions that usually result from AIDS or HIV disease. It will not keep you from spreading HIV to other people. This medicine is available only with your doctor's prescription. Efavirenz is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body. Efavirenz is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Drug information about efavirenz for patients: important things to know, what to tell your doctor before using, how to use, side effects, and more. Find patient medical information for Efavirenz (Sustiva) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings.