Erythromycin Topical is a prescription medication used for the treatment of acne vulgaris. Erythromycin, Eythromycin stearate, Erythromycin ethyl succinate, Erythromycin esolate, Erythromycin base. Authoritative facts from DermNet New Zealand. Topical erythromycin is a prescription treatment for acne that helps reduce bacteria and inflammation. Learn how it works, its side effects, and how to use it effectively. Find patient medical information for Erythromycin topical (Ery, Erygel) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Includes Erythromycin (Topical) indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. Erythromycin Topical Solution Description Erythromycin topical solution, USP 2% contains erythromycin, USP for topical dermatologic use. Erythromycin is a macrolide antibiotic produced from a strain of Saccaropolyspora erythraea (formerly Streptomyces erythreus). It is a base and readily forms salts with acids. Erythromycin (Erygel) is an effective topical antibiotic medication used to treat acne. Similar to other topical acne medications, it can cause peeling, burning, and dryness of the skin. It can take up to 8 weeks to see any improvements in your acne. Erythromycin topical side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Erythromycin topical may cause serious side effects. Call your doctor at once if you have: severe burning, stinging, or redness; oozing or other signs of skin infection; worsening of your skin condition; or severe. Transfer your prescription for ERYTHROMYCIN 2 % GEL on Amazon Pharmacy. FREE SHIPPING for Prime members. For patients using the pledget (swab), topical gel, or topical liquid form of erythromycin: If your doctor has ordered another medicine to be applied to the skin along with this medicine, it is best to wait at least 1 hour before you apply the second medicine. This may help keep your skin from becoming too irritated.