The project that produced piroxicam began in 1962 at Pfizer; the first clinical trial results were reported in 1977, and the product launched in 1980 under the brand name Feldene. [7][12] Major patents expired in 1992 [7] and the drug is marketed worldwide under many brandnames. What Is Feldene? Feldene (piroxicam) is a nonsteroidal anti-inflammatory drug (NSAID) indicated for the relief of the signs and symptoms of osteoarthritis and rheumatoid arthritis. What Are Side Effects of Feldene? Feldene may cause serious side effects including: pounding in neck or ears, drowsiness, blurred vision, swelling, rapid weight gain, Feldene belongs to the group of nonsteroidal anti-inflammatory drugs (NSAIDs) and contains the active ingredient Piroxicam. It works by blocking the production of substances in the body called prostaglandins, which are responsible for causing pain, fever, and inflammation. NSAIDs, including FELDENE, cause serious gastrointestinal (GI) adverse events including inflammation, bleeding, ulceration, and perforation of the esophagus, stomach, small intestine, or large. Overview: Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID). It is used for arthritis symptoms like pain and swelling. Common side effects include nausea, vomiting, constipation or. This information—including product information—is intended only for residents of the United States. The products discussed herein may have different labeling in different countries. Piroxicam (Feldene) is a nonsteroidal anti-inflammatory drug (NSAID) that works well to relieve symptoms of arthritis, such as joint pain, swelling, and stiffness. It's a capsule that's taken by mouth, typically once daily. Possible side effects include diarrhea, nausea, vomiting, and rash. Feldene Gel, generally called as Piroxicam, is the brand name of a non-steroidal anti-inflammatory agent (NSAID) along with analgesic and antipyretic properties. It is topically used for treating acute soft tissue injuries like sprains, strains and tendonitis no more than two weeks. Medscape - Indication-specific dosing for Feldene (piroxicam), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost. What is Feldene? Feldene is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat pain or inflammation caused by osteoarthritis or rheumatoid arthritis. Feldene may also be used for purposes not listed in this medication guide.