Indicated for acute and maintenance treatment of major depressive disorder (MDD) Initial: 20 mg PO qDay. May consider gradually increasing dose after several weeks by 20 mg/day; not to exceed 80. In the controlled clinical trials of fluoxetine supporting its effectiveness in the treatment of Panic Disorder, patients were administered fluoxetine doses in the range of 10 to 60 mg/day. Learn the typical dosages of fluoxetine (Prozac) for depression, OCD, and panic disorder. Find details on available strengths (10mg, 20mg, 40mg), daily timing, and what to do if you miss a dose. Detailed Fluoxetine dosage information for adults and children. Includes dosages for Depression, Panic Disorder, Obsessive Compulsive Disorder and more; plus renal, liver and dialysis adjustments. Find patient medical information for Fluoxetine (Prozac, Sarafem, others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings 40mg of fluoxetine is considered a moderate maintenance dose in adults for major depressive disorder (MDD) and OCD. The standard starting dose for most conditions is 20mg per day, except for panic disorder, which starts at 10mg. The dosage of Prozac (fluoxetine) may vary based on your age and the condition it’s used to treat. The typical starting dosage ranges from 10 to 60 milligrams (mg) per day. Prozac (fluoxetine) can treat certain mental health conditions. A typical Prozac dose is 20 mg daily at first. Your healthcare provider may recommend a greater amount. However, the dose is usually not more than 50 mg of fluoxetine and 12 mg of olanzapine per day. Children younger than 10 years of age—Use and dose must be determined by your doctor. Prozac (Fluoxetine) Dosing Recommendations The recommended starting dose of Prozac is 20 mg once daily in the morning for most indications, with adjustments based on the specific condition being treated. 1.