One common solution that many pet owners turn to is Benadryl. But how much Benadryl can you give a 10 pound dogIn this article, we will explore the recommended dosage, potential side effects, and answer some common concerns related to giving Benadryl to your small canine companion. **Recommended Dosage** Calculate your pet's minimum and maximum dosage of diphenhydramine antihistamine, Benadryl®, with this easy-to-use calculator. How much Benadryl can I give my dog? Calculate the safe diphenhydramine dose based on your dog's weight. Free Benadryl dose for dogs calculator with dosage chart for allergies, itching, and anxiety. How much Benadryl do I give to a 50 lb dog? You should give 50 mg of Benadryl to a 50 lb dog, either as two 25 mg tablets, four 12.5 mg chewable tablets, or 20 ml of a Benadryl liquid form (12.5 mg/5 ml). Benadryl dosage for dogs by weight (lbs) chart The correct Benadryl dosage for dogs should be based on your dog's weight. A simple rule of thumb is to give 1 mg of Benadryl per 1 lb of body weight every 8 to 12 hours. This simple 1:1 dosage is easy to remember, but you can always ask your vet if you're unsure about the correct dosage. Vet-approved Benadryl dosage chart for all dog breeds (Small, Medium & Large). Calculate the exact safe dose (mg) per pound for your pet. Tablet & liquid guide. Benadryl (Diphenhydramine) dose by weight: enter your dog's weight for the exact mg dose, tablet count, and how often. Vet-reviewed sources. Learn about Benadryl for dogs, including how much you can give your dog and if it's safe, with expert insights from a veterinarian. A Quick Tip: How Much Benadryl Can You Give Your Dog? The maximum dose of Benadryl that I recommend is 4 milligrams per kilogram of body weight (i.e. 4mg/kg). Some guidelines: A small dog weighing around 10 pounds (4.5 kg) should receive no more than 18 mg. A medium-sized dog weighing 25 pounds (11.3 kg) could be given up to 45 mg. How Much Benadryl Can I Give My Dog? The standard Benadryl dosage for dogs is 1 mg of Benadryl per pound of body weight, given 2 to 3 times daily (every 8–12 hours). Most veterinarians follow this guideline when recommending over-the-counter dog antihistamines like Benadryl for pets experiencing allergies, itching, insect bites, or mild reactions. Children's Liquid Benadryl formulation is.