Hydroxyzine is used for the short-term treatment of nervousness and tension that may occur with certain mental/mood disorders. Learn about side effects, drug interactions, dosages, warnings, and more. Overview: Hydroxyzine is an antihistamine that is used for certain types of anxiety, itching due to allergic conditions, to help you relax before and after general anesthesia, or for nausea and. Hydroxyzine is used to help control anxiety and tension caused by nervous and emotional conditions. It can also be used to help control anxiety and produce sleep before surgery. Hydroxyzine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms. Hydroxyzine is an antihistamine with anticholinergic (drying) and sedative properties that is used to treat allergic reactions. Hydroxyzine is used for the relief of pruritus (itching) caused by various allergic conditions. Hydroxyzine is used to treat anxiety, tension, itching from allergic skin reactions, and sedation. Learn about doses, side effects, interactions, and uses Learn how hydroxyzine is used for anxiety, its benefits and risks, common side effects, and when it may or may not be the right treatment option. Detailed Hydroxyzine dosage information for adults and children. Includes dosages for Anxiety, Nausea/Vomiting, Sedation and more; plus renal, liver and dialysis adjustments. Hydroxyzine is an antihistamine used to treat allergy symptoms and more. Learn how to use hydroxyzine for anxiety, its dosage, and potential side effects. Hydroxyzine, sold under the brand names Atarax (as hydrochloride) and Vistaril (as pamoate) among others, is an antihistamine medication. It is used in the treatment of itchiness, anxiety, insomnia, and nausea (including that due to motion sickness).