Don’t take more than 1,200 milligrams of ibuprofen a day, unless directed by a provider. If you need it longer than 10 days, seek medical attention. Ibuprofen tablets are contraindicated in patients with known hypersensitivityto ibuprofen. Ibuprofen tablets should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin orother NSAIDs. Severe heart failure and severe kidney disease are contraindications, as ibuprofen can worsen these conditions by increasing fluid retention and reducing renal function. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Avoid taking ibuprofen after a recent heart attack, unless your doctor tells you to. Ibuprofen may also cause stomach or intestinal bleeding, which can be fatal. View ibuprofen information, including dose, uses, side-effects, renal impairment, pregnancy, breast feeding, contra-indications and important safety information. A: Ibuprofen, such as Advil, Motrin or Ibuprofen, can cause marked worsening of existing hypertension (high blood pressure) or development of new high blood pressure. Most adults can use ibuprofen. But ibuprofen is not suitable for everyone. For example, it may not be suitable if: Check the packet or leaflet that comes with your medicine to see if it's suitable for you. Ibuprofen can increase your risk of a heart attack or stroke that can lead to death. This risk is increased in people with existing heart disease and with longer use of ibuprofen and higher. Ibuprofen is absolutely contraindicated in patients with active peptic ulcer disease, chronic kidney disease, heart failure, and in those with the aspirin tr. People who take nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin) such as ibuprofen may have a higher risk of having a heart attack or a stroke than people who do not take these medications. These events may happen without warning and may cause death.