Indication (medicine) In medicine, an indication is a valid reason to use a certain test, medication, procedure, or surgery. [1] There can be multiple indications to use a procedure or medication. [2] An indication can commonly be confused with the term diagnosis. INDICATION definition: anything serving to indicate or point out, as a sign or token. See examples of indication used in a sentence. Indication Today's crossword puzzle clue is a quick one: Indication. We will try to find the right answer to this particular crossword clue. Here are the possible solutions for Indication clue. It was last seen in American quick crossword. We have 12 possible answers in our database. By surface analysis, indicate +‎ -ion. indication (countable and uncountable, plural indications) An act of pointing out or indicating. There's no indication that the fire was caused by criminals. All the indications point to drink-driving as the cause of the accident. INDICATION definition: 1. a sign that something exists, is true, or is likely to happen: 2. a suitable action that is…. Learn more. Define indication. indication synonyms, indication pronunciation, indication translation, English dictionary definition of indication. n. 1. The act of indicating: His indication of refusal came in the form of a frown. 2. Something that serves to indicate; a sign: indications of an economic. Synonyms for INDICATION: clue, hint, suggestion, cue, idea, sign, intimation, inkling; Antonyms of INDICATION: solution, answer The meaning of INDICATION is something that serves to indicate. How to use indication in a sentence. An indication is like a clue, or a suggestion, but it's not proof. If someone is weaving all over the place when they walk, that could be an indication that they’re drunk. INDICATION meaning: 1. a sign that something exists, is true, or is likely to happen: 2. a suitable action that is…. Learn more.