Fluoxetine (Prozac) is a prescription antidepressant used to treat depression, OCD, bulimia, panic disorder, and PMDD. Learn about uses, dosage, side effects, and warnings. Fluoxetine is an antidepressant that belongs to a group of medicines called serotonin selective reuptake inhibitors (SSRIs). It works by increasing the amount of a natural chemical called. Fluoxetine is in a class of medications called selective serotonin reuptake inhibitors (SSRIs). It works by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance. Fluoxetine is a type of antidepressant called a selective serotonin reuptake inhibitor (SSRI). It's thought to work by increasing the level of serotonin (a chemical in the brain linked to mood). What is Fluoxetine (Prozac)? Fluoxetine, also known as Prozac, Serafem and Selfemra, is a selective serotonin reuptake inhibitor (SSRI) that works by increasing the amount of serotonin in the brain. Fluoxetine, sold under the brand name Prozac, among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [2] used for the treatment of major depressive disorder, anxiety, obsessive–compulsive disorder (OCD), panic disorder, premenstrual dysphoric disorder, and bulimia nervosa. [2] Prozac (fluoxetine) is an SSRI antidepressant used to treat depression, OCD, panic disorder, bulimia, and PMDD by boosting serotonin levels in the brain. Prozac is the brand name for an antidepressant medication called fluoxetine. The Federal Drug Administration (FDA) has approved it for treating several conditions, including depression, bulimia, obsessive-compulsive disorder, and panic disorder. Fluoxetine is an oral drug that is used primarily for treating depression. Fluoxetine is also used to treat depression, bulimia, obsessive-compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder (PMDD). Fluoxetine is an antidepressant and belongs to a group of medicines known as selective serotonin reuptake inhibitors (SSRIs). This medicine works by increasing the activity of a chemical called serotonin in the brain. This medicine is available only with your doctor's prescription.