Learn what Percocet is, how it works for pain relief, common side effects, and risks. Plus, treatment options if you're concerned about dependency. Percocet is a prescription painkiller combining oxycodone and acetaminophen. It's used for severe pain when other non-opioid pain treatments haven't worked or cannot be tolerated. Includes Percocet side effects, interactions, and indications. Percocet is still prescribed, but less often. Here’s how opioid guidelines, safety concerns, and new alternatives have changed how doctors approach pain relief. Percocet (oxycodone / acetaminophen) is a controlled substance, which means that it's more likely to be misused or cause dependence. There are federal and state laws that limit the amount of medication that can be prescribed or dispensed within a certain period of time. Find patient medical information for Oxycodone/Acetaminophen (Percocet, Tylox, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Percocet package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology. Oxycodone and Percocet are not the same. Oxycodone contains one medication, while Percocet is a combination of oxycodone and acetaminophen. Review more differences here. Percocet is a prescription medication used for the management of pain severe enough to require an opioid analgesic and for which alternatives are inadequate. Percocet (Oxycodone and Acetaminophen) may treat acute and moderate-to-server pain, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and drug imprint. Percocet is an opioid, though not technically an opiate in the strict pharmacological sense. The distinction matters: opiates are natural compounds derived directly from the opium poppy, like morphine and codeine. Percocet’s active pain-relieving ingredient, oxycodone, is a semi-synthetic opioid, meaning it’s created through chemical modification of a naturally occurring poppy compound.