Your Globulin level of 4 is a Normal Globulin level. Normal Globulin levels may indicate underlying health problems. The normal range is typically between 2 g/dL and 4.1 g/dL. If your levels are outside this range, it's important to speak with a healthcare provider. High globulin means the calculated globulin fraction on the CMP is above the normal upper limit (typically above 4.5 g/dL). The most common causes are chronic infections (such as hepatitis or HIV), autoimmune conditions (such as lupus), inflammatory diseases, and liver disease. This test measures the levels of gamma globulins and other trace proteins found in blood serum. Gamma globulins (also called immunoglobulins) help the immune system fight off foreign substances and infections. A globulin blood test measures a group of proteins that includes your immune antibodies and transport. Normal range, test cost, and where to get tested. Once a globulin blood test is done, the results are compared against the globulin normal range to assess whether the levels are within the expected limits. Abnormalities may indicate a range of health concerns, depending on whether the levels are too high or too low. Globulin levels are determined by subtracting albumin from total protein, also known as the “ gamma gap.” The normal range of globulin is around 2.0-3.9 g/dL or 20-39 g/L. The proper globulin to albumin ratio is 1:2, though this can range from 1.7-2.2 and still remain healthy. If this ratio changes to an extreme level, it can cause a number of health concerns. The albumin globulin ratio calculator will compute the A/G ratio based on your blood test and describe the results. High Globulin 4.4 g/dL indicates that the globulin level is above the normal range and may be associated with increased immune activity, inflammation, infection, or changes in protein production. Medical unit conversion calculator, medicalunitconverter.com. Convert US units to International (SI) units easily with this onlne calculator. Easily search for a specific lab test, enter any value and convert the units.