Learn about vardenafil usage and dosing. Read the latest news and reviews about the drug as well as potential side effects and popular alternatives. Levitra (vardenafil hydrochloride) is an oral medication taken to treat erectile dysfunction (ED). It’s in the same class of drugs as other popular ED medications, including Viagra and Cialis. Description Vardenafil is used to treat men with erectile dysfunction (sexual impotence). It belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where this enzyme works. Erectile dysfunction is a condition where the penis does not harden and expand. Vardenafil's indications and contraindications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different. Find patient medical information for Vardenafil (Levitra, Staxyn) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Viagra and Cialis are oral medications for treating erectile dysfunction. Check out side-by-side comparisons of these ED pills. Levitra relaxes muscles and increases blood flow to particular areas of the body and is used to treat erectile dysfunction. Learn about side effects, interactions and indications. Vardenafil: side effects, dosage, interactions, FAQs, reviews. Used for: erectile dysfunction Levitra is a phosphodiesterase 5 (PDE5) inhibitor taken by mouth for the treatment of erectile dysfunction (ED) in men. Vardenafil is a medication that treats erectile dysfunction. ED is the inability to achieve and sustain an erection suitable for sexual intercourse.