Levofloxacin is used for the treatment of pneumonia, urinary tract infections, and abdominal infections. Learn about the side effects of levofloxacin, from common to rare, for consumers and healthcare professionals. Find patient medical information for Levofloxacin (Levaquin) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Levofloxacin (Levaquin) is an antibiotic that treats bacterial infections. It doesn’t treat colds, the flu or viral infections. Levofloxacin is in a class of antibiotics called fluoroquinolones. It works by killing bacteria that cause infections. Antibiotics such as levofloxacin will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment. Levofloxacin is also used to treat and prevent plague (including pneumonic and septicemic plague). Levofloxacin belongs to the class of medicines known as quinolone antibiotics. Levofloxacin is a fluoroquinolone antibiotic used to treat serious bacterial infections and prevent anthrax or plague exposure when safer options aren't suitable.