Antidepressants such as Lexapro and Zoloft can have sexual side effects. Learn more about how to reduce sexual dysfunction associated with antidepressants. If you experience any sexual problems while taking an SSRI medication, talk with your doctor or therapist. If medication is the problem, sexual side effects sometimes subside with time, so it's worth waiting a while to see if problems diminish. This is a particularly good strategy if the medication is easing your depression significantly. Lexapro may cause sexual side effects like reduced libido or difficulty climaxing for women. Learn about these effects, their causes, and how to manage them ahead. Sexual side effects are common with antidepressants in both men and women, but there are options to prevent or reduce such side effects. Discover how Lexapro may cause erectile dysfunction. Learn about its sexual side effects, why they happen, and how to manage them effectively. Sexual Dysfunction with Lexapro (Escitalopram) Compared to Other SSRIs Lexapro (escitalopram) has significant rates of sexual dysfunction similar to other SSRIs, with approximately 7% of patients experiencing decreased libido and 12-14% of males experiencing ejaculatory disorders, though these rates are likely underreported. 1 Selective serotonin reuptake inhibitors (SSRIs) like Lexapro are powerful tools in managing depression and anxiety. However, they can sometimes impact sexual function in complex ways. Understanding these potential side effects helps patients make informed decisions about their mental health treatment. While sexual side effects are common with antidepressants, some types and doses are less likely to cause them. If you’re experiencing sexual side effects from Lexapro, there are strategies you can try to prevent or reduce them. If you experience Lexapro sexual side effects, your healthcare provider may recommend a change in dosage, timing for taking the medication, or to another medication. Additional coping strategies, such as talking to your partner and therapy, can help you cope with these side effects. Sexual dysfunction: mentioned by 208 users (8.6%) Based on user experiences from 2,421 Lexapro reviews, the following table shows the most commonly mentioned side effects. All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.