Lisinopril is an ACE inhibitor used to treat high blood pressure and heart conditions. Learn about its uses, side effects, and precautions. Lisinopril is an oral medication used to treat high blood pressure and heart failure. Learn about side effects, warnings, dosage, and more. Find patient medical information for Lisinopril (Prinivil, Zestril, and Others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Lisinopril is used alone or in combination with other medications to treat high blood pressure in adults and children 6 years of age and older. It is used in combination with other medications to treat heart failure. Lisinopril is also used to improve survival after a heart attack. Lisinopril is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It works by. Detailed Lisinopril dosage information for adults, the elderly and children. Includes dosages for Hypertension, Congestive Heart Failure, Myocardial Infarction and more; plus renal, liver and dialysis adjustments. Lisinopril works by blocking a substance in the body that causes the blood vessels to tighten. As a result, lisinopril relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart. Lisinopril is also used to help treat heart failure. It is also used in some patients after a heart attack. Lisinopril is an ACE inhibitor. It is used to treat high blood pressure, congestive heart failure in adults, or to improve survival after a heart attack. Lisinopril is a medication belonging to the drug class of angiotensin-converting enzyme (ACE) inhibitors and is used to treat hypertension (high blood pressure), heart failure, and heart attacks. [7] For high blood pressure it is usually a first-line treatment. It is also used to prevent kidney problems in people with diabetes mellitus. [7] Lisinopril is taken orally (swallowed by mouth). [7. Lisinopril is a prescription generic medication used to treat high blood pressure (hypertension). Learn about side effects, drug interactions, dosages, warnings, and more. Lisinopril (Zestril, Qbrelis) is an angiotensin-converting enzyme (ACE) inhibitor. It’s prescribed to treat high blood pressure, heart failure, and heart attacks. Common lisinopril side effects include low blood pressure, dizziness, and headache. Some people may experience a dry cough from lisinopril that requires them to stop taking it.