Medscape - Diabetes type 2-specific dosing for Glucophage, Glucophage XR (metformin), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation. Metformin, a staple of glucose management for decades, is now being studied for use in a wide range of diseases from carotid atherosclerosis to vitiligo. Metformin is used to treat high blood sugar levels that are caused by a type of diabetes mellitus or sugar diabetes called type 2 diabetes. With this type of diabetes, insulin produced by the pancreas is not able to get sugar into the cells of the body where it can work properly. This article describes the dosages of metformin, as well as its strengths and how to take it. When taking metformin, always follow the dosage prescribed by your doctor. See recommended Metformin doses by age and product type. Learn about IR, ER, combos, dose adjustments, and tips for taking Metformin safely. Detailed Metformin dosage information for adults and children. Includes dosages for Diabetes Type 2; plus renal, liver and dialysis adjustments. Below is a complete guide to metformin dosing across all major use cases covering standard diabetes therapy, weight loss, prediabetes prevention, and special population adjustments backed by current clinical evidence and prescribing guidelines from the FDA prescribing information for metformin. What is metformin used for? Metformin is used to help lower blood sugar levels in people with type 2 diabetes. Metformin may also be used for other conditions as determined by your health. Metformin is an FDA-approved antidiabetic agent that manages high blood sugar levels in type 2 diabetes patients. It reduces glucose absorption from the intestines, lowers liver glucose production, and improves insulin sensitivity. A general discussion of initial treatment of type 2 diabetes and the role of metformin in the prevention of diabetes, in the treatment of polycystic ovary syndrome, and in gestational diabetes are reviewed separately.