Description Metformin is used together with proper diet and exercise to treat high blood sugar levels caused by type 2 diabetes. This medicine reduces the absorption of sugar from the intestines, reduces the release of stored sugar from the liver, and helps your body use sugar better. Many people can control type 2 diabetes with diet and exercise. Following a specially planned diet and. Metformin hydrochloride extended-release tablets, USP contains 500 mg of metformin hydrochloride, which is equivalent to 389.93 mg metformin base. Metformin hydrochloride extended-release tablets USP, 500 mg contain the inactive ingredients carboxymethylcellulose sodium, hypromellose and magnesium stearate. Learn how metformin treats type 2 diabetes, including dosage, side effects, warnings, and its off-label use for weight loss and PCOS. Reviewed drug info Metformin Extended Release Tablets package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology. Learn about metformin ER usage and dosing. Read the latest news and reviews about the drug as well as potential side effects and popular alternatives. The difference between Metformin IR and ER goes beyond dosing. Compare release mechanisms, patient adherence, and managing common gastrointestinal side effects. Metformin ER 500 mg treats type 2 diabetes and PCOS by reducing liver glucose output. Learn how it works, who it helps, and what to watch for long-term. Metformin can cause changes in the menstrual cycle (promote ovulation) and increase the risk of becoming pregnant. Consult your doctor or pharmacist about the use of reliable birth control while using this medication. Metformin passes into breast milk in small amounts. Consult your doctor before breastfeeding. Metformin is effective for managing diabetes. But is metformin extended-release (ER) better for you? See the differences between metformin versus metformin ER. Metformin Extended-Release Tablets What is this medication? METFORMIN (met FOR min) treats type 2 diabetes. It controls blood sugar (glucose) and helps your body use insulin effectively. Changes to diet and exercise are often combined with this medication.