Metoprolol is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. Metoprolol tartrate is indicated for the treatment of hypertension in adult patients, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions. Lopressor (metoprolol tartrate) Tablets and Injection is a selective beta-adrenoreceptor blocking agent (beta-blocker) used to treat high blood presure (hypertension), angina, and heart attacks. Find patient medical information for Metoprolol (Lopressor, Toprol XL, others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings The main difference between metoprolol tartrate and metoprolol succinate is that metoprolol tartrate is only available as an immediate-release tablet which means it must be taken several times per day, whereas metoprolol succinate is an extended-release tablet that can be taken once a day. Easy-to-read patient tips for metoprolol-tartrate covering how it works, benefits, risks, and best practices. In controlled clinical trials, metoprolol tartrate, administered two or four times daily, has been shown to be an effective antianginal agent, reducing the number of angina attacks and increasing exercise tolerance. The dosage used in these studies ranged from 100 to 400 mg daily. Acute Myocardial Infarction Metoprolol tartrate is used orally and IV to reduce the risk of cardiovascular mortality in hemodynamically stable patients with definite or suspected acute MI. The term MI is used when there is evidence of myocardial necrosis in the setting of acute myocardial ischemia. [807] The specific agent in on-market formulations of metoprolol is either metoprolol tartrate or metoprolol succinate, where tartrate is an immediate-release formulation and the succinate is an extended-release formulation (with 100 mg metoprolol tartrate corresponding to 95 mg metoprolol succinate). Titrate dosage based on tolerability and hemodynamic parameters (i.e., heart rate, blood pressure). Metoprolol Tartrate Tablets should preferably be administered with or following meals. The maximum daily maintenance dosage is 100 mg orally twice daily.