Metronidazole gel and cream are antimicrobial skin preparations. They are used to treat rosacea or to reduce unpleasant smells from infected wounds. For rosacea, apply a thin layer twice daily, usually for weeks or months. For wounds, it is usually applied once or twice daily after cleaning. MetroCream (Metronidazole Topical Cream) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Find patient medical information for Metronidazole topical on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Metronidazole cream is a medication that treats rosacea by decreasing inflammation and destroying bacteria growth on your skin. Rosacea causes redness and inflammation on your face. Metronidazole is a nitroimidazole with antiprotozoal, antibacterial, and anti-inflammatory properties and is available in oral and topical formulations. The diverse mechanisms of action of metronidazole have expanded its utility across various dermatologic conditions. Apply and rub in a thin layer of metronidazole topical cream twice daily, morning and evening, to entire affected areas after washing. Areas to be treated should be washed with a mild cleanser before application. Metronidazole is in a class of medications called nitroimidazole antimicrobials. It works by stopping the growth of bacteria. How should this medicine be used? Metronidazole comes as a cream, lotion, or gel to be applied to your skin. Apply once or twice a day. Use metronidazole exactly as directed. Metronidazole is a nitroimidazole antimicrobial that kills anaerobic bacteria and parasites via DNA-damaging free radicals. It treats trichomoniasis, amebiasis, and serious anaerobic infections, and prevents post-colorectal-surgery infection. Learn about side effects, interactions, and indications. What is metronidazole topical? Metronidazole topical (for the skin) is used to treat skin lesions caused by rosacea. Metronidazole topical may also be used for purposes not listed in this medication guide. Description Metronidazole topical gel is used to treat inflammatory lesions (pimples and red bumps) caused by rosacea. Rosacea is a skin disease that causes redness and pimples on your nose, cheeks, chin, and forehead. This medicine is available only with your doctor's prescription.