Find patient medical information for Metronidazole topical on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Metronidazole is an antibiotic that may be used to treat certain infections of the vagina, stomach, liver, skin, joints, brain and spinal cord, lungs, heart, or bloodstream. Metronidazole topical is a medication used for the treatment of various skin conditions caused by certain types of bacteria or parasites. It is available in the form of a gel, cream, or lotion, and is applied directly to the affected area of the skin. Find drug information for Metronidazole - Topical on CVS.com, including related drug classes, side effects, dosage, and answers to frequently asked questions. What is metronidazole topical? Metronidazole topical (for the skin) is used to treat skin lesions caused by rosacea. Metronidazole topical may also be used for purposes not listed in this medication guide. Metronidazole cream, gel, and lotion are for topical use only and patients should apply a thin layer to the afected areas once-twice daily. Studies have demonstrated that for both the 0.75% and 1% formulations, once daily application of topical metronidazole is as efective as twice daily application. Metronidazole gel USP (topical), 0.75%, is indicated for topical application in the treatment of inflammatory papules and pustules of rosacea. Description Metronidazole topical gel is used to treat inflammatory lesions (pimples and red bumps) caused by rosacea. Rosacea is a skin disease that causes redness and pimples on your nose, cheeks, chin, and forehead. This medicine is available only with your doctor's prescription. Metronidazole is a nitroimidazole with antiprotozoal, antibacterial, and anti-inflammatory properties and is available in oral and topical formulations. The diverse mechanisms of action of metronidazole have expanded its utility across various dermatologic conditions. Metronidazole Topical: learn about side effects, dosage, special precautions, and more on MedlinePlus.