Mifepristone combined with misoprostol is the preferred medication regimen for management of early pregnancy loss. While misoprostol alone can be used, the addition of a dose of mifepristone twenty-four hours before misoprostol administration improves treatment efficacy. [29] Find patient medical information for Mifepristone (Mifeprex) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Mifepristone is used in combination with misoprostol (Cytotec ®) to end an early pregnancy. Mifepristone is in a class of medications called antiprogestational steroids. It works by blocking the activity of progesterone, a substance your body makes to help continue pregnancy. Mifepristone is also available as another product (Korlym ®), which is used to control hyperglycemia (high blood. Mifepristone, also called “the abortion pill,” is a U.S. FDA-approved oral medication used—along with misoprostol—in a two-drug regimen to end a pregnancy up to 70 days into gestation. Decades of evidence have shown that mifepristone is extremely safe and very effective, says Carolyn Sufrin. The Supreme Court has restored broad access to the abortion pill mifepristone, blocking a ruling that had threatened to upend one of the main ways abortion is provided across the nation. The Food and Drug Administration (FDA) is moving ahead with a safety review of the abortion pill mifepristone, according to an administration official. The move marks a victory for anti-abortion gr… Questions and Answers on Mifeprex General Information What is mifepristone and how does it work? Mifepristone is a drug that blocks a hormone called progesterone that is needed for a pregnancy to. RU-486 is the former name of mifepristone — one of the medications that you take to have a medication abortion. RU-486 is now called the abortion pill or Mifeprex (the brand name for mifepristone). Description Mifepristone is used in a regimen together with misoprostol to end a pregnancy that is less than 70 days in duration. It works by stopping the supply of hormones that maintains the interior of the uterus. Without these hormones, the uterus cannot support the pregnancy and the contents of the uterus are expelled. Mifepristone is also used to control high blood sugar (hyperglycemia. Mifepristone (Mifeprex) is an oral tablet that may be used with misoprostol tablets to end a pregnancy that is 10 weeks or less (70 days or less since the start of your last period). Another brand of mifepristone called Korlym may be used to treat high blood sugar caused by high cortisol levels in adults with Cushing’s syndrome who have type 2 diabetes or glucose intolerance and have failed.