Misoprostol by mouth is the least effective treatment for producing complete abortion in a period of 24 hours due to the liver's first-pass effect which reduces the bioavailability of the misoprostol. Learn how to safely use misoprostol for an abortion, including dosage, protocol, expected symptoms, side effects, and precautions. Get detailed guidance for a safe abortion process. This page talks about having an abortion using only misoprostol — it's safe, effective, and legal to use in states where abortion is legal. It works 85-95% of the time and can be used up to 12 weeks from the first day of your last period. Find patient medical information for Misoprostol (Cytotec) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings However, misoprostol-alone regimens may be the treatment of choice in settings in which mifepristone is not available or is too costly. This topic review will discuss use of misoprostol as a single agent for medical termination of pregnancy. Misoprostol is a synthetic prostaglandin that works by replacing prostaglandins whose production is blocked by aspirin or NSAIDs. It is used to prevent stomach ulcers from developing during treatment with aspirin or an NSAID. There are currently multiple dedicated Misoprostol products on the global medication market. A list and detailed map can be accessed by clicking the link below. Misoprostol is used to decrease the risk of having stomach ulcers in patients taking nonsteroidal anti-inflammatory drugs (NSAIDs) including aspirin. This medicine works by helping the stomach protect itself against acid damage, and decreases the amount of acid produced by the stomach. Misoprostol is a very powerful stimulator of uterine contractions in late pregnancy and can cause fetal death and uterine rupture if used in high doses. Follow the dosage regimes carefully and do not exceed those doses. Misoprostol is used to prevent ulcers in people who take certain arthritis or pain medicines, including aspirin, that can cause ulcers. It protects the stomach lining and decreases stomach acid secretion.