Misoprostol is a synthetic prostaglandin that works by replacing prostaglandins whose production is blocked by aspirin or NSAIDs. It is used to prevent stomach ulcers from developing during treatment with aspirin or an NSAID. Find patient medical information for Misoprostol (Cytotec) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Misoprostol by mouth is the least effective treatment for producing complete abortion in a period of 24 hours due to the liver's first-pass effect which reduces the bioavailability of the misoprostol. Discover Misoprostol: a comprehensive guide covering its uses for ulcer prevention, labor induction, medical abortion, and PPH management. Learn about benefits, side effects, dosage, and safety considerations for this essential medication. Learn how to safely use misoprostol for an abortion, including dosage, protocol, expected symptoms, side effects, and precautions. Get detailed guidance for a safe abortion process. Misoprostol is used to decrease the risk of having stomach ulcers in patients taking nonsteroidal anti-inflammatory drugs (NSAIDs) including aspirin. This medicine works by helping the stomach protect itself against acid damage, and decreases the amount of acid produced by the stomach. Misoprostol is used to prevent ulcers in people who take certain arthritis or pain medicines, including aspirin, that can cause ulcers. It protects the stomach lining and decreases stomach acid secretion.