Safe naproxen (Aleve, Naprosyn) dosages are key to getting the most out of your medication. The maximum dose of over-the-counter (OTC) Aleve is 660 mg (3 pills) per day for adults and adolescents ages 12 and older. There are four main types of oral analgesics that are available without a prescription: naproxen (brand name Aleve), ibuprofen (brand names Advil and Motrin), aspirin, and acetaminophen (brand name Tylenol). Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve symptoms of arthritis (eg, osteoarthritis, rheumatoid arthritis, or juvenile arthritis) such as inflammation, swelling, stiffness, and joint pain. Explains the medication naproxen (Aleve, Naprosyn, Anaprox, Naprelan) a drug used for the management of mild to moderate pain, fever, and inflammation. The article includes descriptions, uses, drug interactions, and side effects. Find out how Aleve (naproxen) can treat pain and inflammation, how much you should take, and its potential side effects. Find patient medical information for Naproxen (Aleve, Naprosyn, others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Naproxen, sold under the brand name Aleve among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, menstrual cramps, and inflammatory diseases such as rheumatoid arthritis, gout and fever. [7] Just one Aleve® is strong enough to provide up to 12 hours of uninterrupted pain relief. Temporarily reduces fever. Do not take more than directed. The smallest effective dose should be used. Drink a full glass of water with each dose. Take one caplet every 8 to 12 hours while symptoms last. Aleve is a nonsteroidal anti-inflammatory drug (NSAID). Naproxen works by reducing hormones that cause inflammation and pain in the body. Aleve is used to temporarily relieve minor aches and pains due to arthritis, muscular aches, backache, menstrual cramps, headache, toothache,and the common cold. Aleve is also used to temporarily reduce fever. Aleve contains naproxen, but they’re not exactly the same thing. Here’s what differs in form, dosage, and what to watch out for.