Neomycin, polymyxin B, and dexamethasone combination is used to treat eye infections and inflammation, including conjunctivitis and chronic anterior uveitis. It also prevents damage caused by chemicals, radiation, or foreign objects entering the eye. Find patient medical information for Neomycin/Polymyxin B/Hydrocortisone otic (Cortisporin Otic, Casporyn HC, Oticair) on WebMD including its uses, side effects and safety, interactions. Neomycin, polymyxin B, and hydrocortisone combination ear drops is used to treat infections of the ear canal and to help provide relief from redness, irritation, and discomfort of certain ear problems. Neomycin, Polymyxin, Hydrocortisone Ear Drops package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology. Neomycin and polymyxin B sulfates are antibiotics often combined in medications to treat various infections. Understanding their uses, dosages, side effects, and different forms is crucial for safe and effective treatment. Pharmaceutical grade neomycin is composed of several related compounds including neomycin A, neomycin B, neomycin C, and a few minor compounds found in much lower quantities. NEOMYCIN; POLYMYXIN B; DEXAMETHASONE (nee oh MYE sin; pol i MIX in B; dex a METH a sone) treats eye swelling, redness, or itching caused by infections, injury, or other conditions. It also prevents and treats eye infections caused by bacteria. It works by killing or preventing the growth of bacteria. Neomycin and Polymyxin B Sulfates package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology. A variant of Polysporin, called Polysporin Triple Ointment, replaces neomycin with gramicidin, providing an alternative for those allergic to neomycin while still offering broad-spectrum coverage against both Gram-negative and Gram-positive bacteria. Neomycin/polymyxin B/dexamethasone ophthalmic kills certain types of bacteria by blocking their ability to create proteins that they need to grow and reproduce and by weakening their cell.