FDA Structured Product Label (SPL) for Oxycodone/apap (NDC 61919-432). Review professional prescribing information, including boxed warning, description, Oxycodone acetaminophen is a prescription drug used for the management of moderate to severe pain. Learn about side effects, dosages, drug interactions, and more. Oxycodone and Acetaminophen Tablets should not be administered to patients with known hypersensitivity to oxycodone, acetaminophen, or any other component of this product. Oxycodone is contraindicated in any situation where opioids are contraindicated including patients with significant respiratory depression (in unmonitored settings or the absence of resuscitative equipment) and patients with. Oxycodone is available in a variety of formulations for by mouth or under the tongue: [10][38][39][40] Immediate-release oxycodone (OxyFast, OxyIR, OxyNorm, Roxicodone, Shortec) Controlled-release oxycodone (OxyContin, Xtampza ER, Oxypro) – 10–12 hour duration [15] Oxycodone tamper-resistant (OxyContin OTR) [41] Immediate-release oxycodone with paracetamol (acetaminophen) (Percocet. Oxycodone and acetaminophen tablets expose patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death. Assess each patient's risk prior to prescribing oxycodone and acetaminophen tablets, and monitor all patients regularly for the development of these behaviors and conditions [see WARNINGS]. Oxycodone and acetaminophen tablets are used to manage pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate, and when other pain treatments such as non-opioid pain medicines do not treat your pain well enough, or you cannot tolerate them. Includes side effects, dosage, and more. Oxycodone/acetaminophen has a risk for abuse and addiction, which can lead to overdose and death. Oxycodone/acetaminophen may also cause severe, possibly fatal, breathing problems. To lower your risk, your doctor should have you take the smallest dose of oxycodone/acetaminophen that works, and take it for the shortest possible time. See also How to Use section for more information about. Oxycodone and acetaminophen combination can cause serious unwanted effects or fatal overdose if taken by children, pets, or adults who are not used to strong opioid pain medicines. Oxycodone 5/325 APAP contains 5mg of oxycodone and 325mg of acetaminophen (tylenol). APAP is an abbreviation of acetyl-para-aminophenol - the chemical name of acetaminophen. Find patient medical information for Oxycodone/Acetaminophen (Percocet, Tylox, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings.