Oxycodone is a medicine used to treat severe pain. It's only available with a prescription. Oxycodone is a type of medicine called an opioid. It's used to treat pain, for example after an operation or a serious injury, or pain from cancer. Learn about oxycodone usage and dosing. Read the latest news and reviews about the drug as well as potential side effects and popular alternatives. Overview: Oxycodone is a medicine that is used to help treat severe pain. Common side effects include constipation, nausea, vomiting, stomach pain, headache, and dizziness. Do not drive or do. Oxycodone is an opioid medication that takes on pain. It comes in tablet, capsule, or liquid form. Understand the uses, side effects, and precautions. Oxycodone is an opioid medication that treats severe pain. It works by blocking pain signals in your brain. Oxycodone is used to relieve pain severe enough to require opioid treatment and when other pain medicines did not work well enough or cannot be tolerated. It belongs to the group of medicines called opioid analgesics (pain medicines). Oxycodone is used to manage pain severe enough to require an opioid pain medicine when other pain medicines do not treat pain well enough, or are not tolerated. Includes oxycodone side effects, dose, reviews, warnings, and more. Oxycodone is a prescription opioid medicine used to manage pain severe enough to require an opioid when other pain treatments do not work well enough or cannot be tolerated. Some forms are used for around-the-clock, long-term pain treatment, while others are used as needed for pain relief. Oxycodone, sold under the brand names Roxicodone and OxyContin (which is the extended-release form) among others, is a semi-synthetic opioid used medically for the treatment of moderate to severe pain. Why is this medication prescribed? Oxycodone is used to relieve severe pain. Oxycodone is in a class of medications called opiate (narcotic) analgesics. It works by changing the way the brain and nervous system respond to pain.