Pantoprazole is a proton-pump inhibitor (PPI) and its effectiveness is similar to that of other PPIs. [11] It is available by mouth and by injection into a vein. Pantoprazole (Protonix) is a proton pump inhibitor (PPI) that lowers stomach acid. It treats erosive esophagitis, or damage to the esophagus caused by gastroesophageal reflux disease (GERD), in adults and certain children. Pantoprazole is a proton pump inhibitor that decreases the amount of acid produced in the stomach. Pantoprazole is used to treat erosive esophagitis (damage to the esophagus from stomach acid caused by gastroesophageal reflux disease, or GERD) in adults and children who are at least 5 years old. Pantoprazole is used to treat certain conditions in which there is too much acid in the stomach. It is used to treat erosive esophagitis or heartburn caused by gastroesophageal reflux disease (GERD), a condition where the acid in the stomach washes back up into the esophagus. Pantoprazole: learn about side effects, dosage, special precautions, and more on MedlinePlus Learn about the side effects of pantoprazole, from common to rare, for consumers and healthcare professionals. Overview: Pantoprazole is used to treat acid reflux and other conditions where you have too much acid in your stomach. It works by reducing how much acid your stomach makes and usually takes a. View pantoprazole information, including dose, uses, side-effects, renal impairment, pregnancy, breast feeding, monitoring requirements and important safety information. Pantoprazole (Protonix) is a medication that treats conditions that cause too much stomach acid, like heartburn, stomach ulcers and reflux disease. Pantoprazole is used to treat certain stomach and esophagus problems (such as acid reflux). It works by decreasing the amount of acid your stomach makes. This medication relieves symptoms such as heartburn, difficulty swallowing, and persistent cough.