Paroxetine oral tablets are used to treat mood and anxiety disorders. It’s also available as the brand-name drugs Paxil, Paxil CR, and Pexeva. Learn about side effects, dosage, warnings, and more. Find patient medical information for Paroxetine (Paxil) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Paroxetine is used to treat depression, obsessive-compulsive disorder (OCD), panic disorder, generalized anxiety disorder (GAD), social anxiety disorder (also known as social phobia), premenstrual dysphoric disorder (PMDD), and posttraumatic stress disorder (PTSD). Paroxetine (Paxil CR) treats depression, anxiety, OCD and PTSD. It increases the amount of serotonin in your brain. Learn about the side effects of paroxetine, from common to rare, for consumers and healthcare professionals. Paroxetine is in a class of medications called selective serotonin-reuptake inhibitors (SSRIs). It treats depression and other mental illnesses by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance. Paroxetine is used to treat depression, panic attacks, anxiety disorders, and a severe form of premenstrual syndrome (premenstrual dysphoric disorder). Learn about side effects, dosages, drug interactions, and more. Paroxetine is an antidepressant that belongs to a group of medicines called selective serotonin reuptake inhibitors (SSRIs). Paroxetine works by increasing levels of serotonin, which helps reduce symptoms of depression and improves mood, anxiety, and other disorders. Paroxetine is a type of antidepressant called a selective serotonin reuptake inhibitor (SSRI). It's thought to work by increasing the level of serotonin (a chemical in the brain that affects mood). Paroxetine is primarily used to treat major depressive disorder, obsessive–compulsive disorder, post-traumatic stress disorder, social anxiety disorder, and panic disorder. It is also occasionally used for agoraphobia, generalized anxiety disorder, premenstrual dysphoric disorder, and menopausal hot flashes. [16][17][18][19][20].