Percocet is a prescription painkiller combining oxycodone and acetaminophen. It's used for severe pain when other non-opioid pain treatments haven't worked or cannot be tolerated. Percocet package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology. Percocet (oxycodone and acetaminophen) is a combination drug consisting of an opioid and a pain reliever and fever reducer (analgesic and antipyretic) used for the management of moderate to severe pain, usually for an extended time period. Oxycodone/acetaminophen is a combination medicine used to treat severe pain. Oxycodone is an opioid that binds to pain receptors; acetaminophen helps block pain signals. Learn what Percocet is, how it works for pain relief, common side effects, and risks. Plus, treatment options if you're concerned about dependency. Percocet is a prescription medication used for the management of pain severe enough to require an opioid analgesic and for which alternatives are inadequate. Learn about Percocet (oxycodone / acetaminophen) usage and dosing. Read the latest news and reviews about the drug as well as potential side effects and popular alternatives. Learn about the various side effects of short- and long-term use of Percocet, the dangers of misuse of Percocet, and how to find treatment. Oxycodone/paracetamol, sold under the brand name Percocet among others, [2] is a fixed-dose combination of the opioid oxycodone with paracetamol (acetaminophen), used to treat moderate to severe pain. Medscape - Pain dosing for Percocet (oxycodone/acetaminophen), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost.