Used mainly for the management of neuropathic pain, pregabalin is a gabapentinoid or anticonvulsant that was initially developed as an antiepileptic agent. What Is Pregabalin and How Does It Work? Pregabalin is used to treat pain caused by nerve damage due to diabetes or to shingles (herpes zoster) infection. It may also be used to treat nerve pain caused by spinal cord injury. This medication is also used to treat pain in people with fibromyalgia. Pregabalin (Lyrica) is a medication that treats nerve pain by calming overactive nerves. It can also treat epilepsy. View pregabalin information, including dose, uses, side-effects, renal impairment, pregnancy, breast feeding and important safety information. Pregabalin is as effective at relieving pain as duloxetine and amitriptyline. Combination treatment of pregabalin and amitriptyline or duloxetine offers additional pain relief for people whose pain is not adequately controlled with one medication and is safe. [48][49] Pregabalin is used to treat fibromyalgia pain; nerve pain from diabetes, shingles or spinal cord injury; and partial-onset seizures, depending on the formulation. Learn about side effects, administration, and interactions. Detailed Pregabalin dosage information for adults and children. Includes dosages for Fibromyalgia, Neuropathic Pain, Diabetic Neuropathy and more; plus renal, liver and dialysis adjustments. Pregabalin is used with other medicines to help control partial-onset seizures (convulsions) in the treatment of epilepsy in patients 1 month of age and older. This medicine will not cure epilepsy and will only work to control seizures for as long as you continue to take it. Pregabalin is used to treat certain types of nerve pain, fibromyalgia, or seizures. Common side effects may include dizziness, sleepiness, fluid retention, and blurred vision. Pregabalin oral capsule is used to treat neuropathic pain and fibromyalgia. Learn about side effects, warnings, dosage, and more.