Located in the heart of Rochester, Minnesota — a dynamic city just 90 minutes south of the Twin Cities of Minneapolis and St. Paul — Mayo Clinic has been safely caring for patients from around the world for more than 100 years. Discover inspiring contemporary art in the heart of downtown Rochester. Located along the scenic Zumbro River, Rochester Art Center features powerful exhibitions by regional, national, and international… Rochester is broadly known for the world-renowned Mayo Clinic, but you don’t need to be checked-in to check out this extraordinary Minnesota destination. From arts to events, shopping, dining and breweries, use this visitors guide to find what to do, where to eat and where to stay when you’re in Rochester. Discover why Rochester, MN, ranks as a best place to live in the U.S., with cost of living, employment, things to do and more. Have you ever found yourself looking for things to do with a few hours to spare while in Rochester, MN? Whether you’re between appointments, tournament games, sporting events, or concert times, Rochester is home to a plethora of activities for the whole family. The city is the home and birthplace of Mayo Clinic. Rochester first developed as a stagecoach stop between Dubuque, Iowa, and Saint Paul, Minnesota. With the creation of the Mayo Clinic in 1864, Rochester became a national center for healthcare, as well as a hub for regional agriculture. [10] Downtown Rochester is transforming. Let us help you navigate the changes. Pools, beaches & splash pads are open for the season. The official website for the City of Rochester. Rochester, city, seat of Olmsted county, southeastern Minnesota, U.S. It lies on the Zumbro River and on several creeks in a mixed-farming region about 75 miles (120 km) southeast of Minneapolis. Rochester, MN, is a city rich with culture, history, and natural beauty. From the renowned Mayo Clinic to the charming parks and museums, there is something for everyone to enjoy. Traveling to Rochester, Minnesota? Find helpful information about hotels, events, restaurants, things to do, and Mayo Clinic visitor information.