Seroquel is used to treat the symptoms of schizophrenia, bipolar disorder and major depressive disorder. Learn about side effects, interactions and indications. Find patient medical information for Quetiapine (Seroquel) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Quetiapine is one of only two antipsychotics (the other is cariprazine) that produce equal efficacy as standalone therapies for mixed manic-depressive mood swings as they do in combination with an SSRI antidepressant. Seroquel is a prescription tablet used to treat bipolar I disorder and certain other mental health conditions. Learn about its dosage, side effects, and more. Quetiapine (Seroquel) is an antipsychotic that treats schizophrenia and bipolar disorder. It balances dopamine and serotonin in your brain. Seroquel's an atypical antipsychotic for the treatment of schizophrenia, Bipolar I disorder (manic, mixed and depressive episodes) and major depressive disorder. Vraylar and Seroquel are both oral prescription medicines known as atypical antipsychotics. They treat the mental health conditions schizophrenia and bipolar disorder. Seroquel is a prescription medicine used to treat the symptoms of Schizophrenia, Bipolar I Disorder, Mania; Bipolar Disorder, Depressive Episodes; Bipolar I Disorder, Maintenance; and Major Depressive Disorder. Seroquel may be used alone or with other medications. Seroquel (quetiapine) is an atypical antipsychotic medication used to treat mental disorders such as depression. Doctors also prescribe it off-label to treat anxiety disorders. Quetiapine is used alone or together with other medicines to treat bipolar disorder (depressive and manic episodes) and schizophrenia. Quetiapine extended-release tablet is also used together with other antidepressants to treat major depressive disorder.